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Photodiagnosis of the Serum Samples of Differentiated Thyroid Carcinoma Patients: A Pilot Study

Published on February 2013 by Sudha D. Kamath, Srujan K, Nandini Pandit
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International Conference on Electronic Design and Signal Processing
Foundation of Computer Science USA
ICEDSP - Number 1
February 2013
Authors: Sudha D. Kamath, Srujan K, Nandini Pandit
c1f92ef4-8584-47b4-87ca-0736c2c17952

Sudha D. Kamath, Srujan K, Nandini Pandit . Photodiagnosis of the Serum Samples of Differentiated Thyroid Carcinoma Patients: A Pilot Study. International Conference on Electronic Design and Signal Processing. ICEDSP, 1 (February 2013), 4-6.

@article{
author = { Sudha D. Kamath, Srujan K, Nandini Pandit },
title = { Photodiagnosis of the Serum Samples of Differentiated Thyroid Carcinoma Patients: A Pilot Study },
journal = { International Conference on Electronic Design and Signal Processing },
issue_date = { February 2013 },
volume = { ICEDSP },
number = { 1 },
month = { February },
year = { 2013 },
issn = 0975-8887,
pages = { 4-6 },
numpages = 3,
url = { /specialissues/icedsp/number1/10345-1002/ },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Special Issue Article
%1 International Conference on Electronic Design and Signal Processing
%A Sudha D. Kamath
%A Srujan K
%A Nandini Pandit
%T Photodiagnosis of the Serum Samples of Differentiated Thyroid Carcinoma Patients: A Pilot Study
%J International Conference on Electronic Design and Signal Processing
%@ 0975-8887
%V ICEDSP
%N 1
%P 4-6
%D 2013
%I International Journal of Computer Applications
Abstract

Tg is a specific and sensitive marker for the presence of functioning thyroid tissue, and its measurement is fundamental in the follow-up of patients affected by differentiated thyroid carcinomas (DTCs). Serum antibodies against thyroglobulin (TgAbs) are common in patients with DTC and can interfere in thyroglobulin (Tg) assays. Unfortunately, serum Tg measurement becomes useless in approximately 10–20% of DTC cases who are positive for anti-Tg antibodies that interfere with the Tg measurement. To overcome this problem, in the present study, we have used absorption spectroscopy technique for the quantification of Tg and TgAb.

References
  1. P. M. Clark, 2009. Laboratory services for thyroglobulin and implications for monitoring of differentiated thyroid cancer, J Clin Pathol: 62,402-406.
  2. W. H. Moretz III, C. G. Gourine, D. J. Terris, Z. S. Xia, Z. Liu, P. M. Weinberger, E. Chin, B. L. Adam, 2008. Detection of Papillary thyroid Carcinoma With Serum Protein Profile analysis, Arch Otolaryngol Head Neck surg. 134 (2), 198-202.
  3. P. Caturegli, R. C. Kuppers, S. Mariotti, C. L. Burek, A. Pinchera, P. W. Ladenson and N. R. Rose 1994. IgG subclass distribution of thyroglobulin antibodies in patients with thyroid disease, Clin Exp Immunol. , 98, 464-469.
Index Terms

Computer Science
Information Sciences

Keywords

Thyroglobulin Thyroglobulin Antibody Absorption Immunoglobulin Antibody G (igg)