In this paper, two configurations of Operational Transconductance Amplifier (OTA), namely Current Mirror and Telescopic are designed and compared on the basis of voltage gain, slew rate and Common Mode Rejection Ratio (CMRR). The design simulation is done using Cadence Analog Design Environment with 0. 18µm technology node. Emphasis is laid on reduced power design as analog or mixed signal IC's require low power and low area circuits. OTA forms the basic building block in many analog circuits and replaces Op-amps. Active filter circuits, Power System on a Chip (PSoC), Bio-signal Amplifiers etc. are designed using OTAs. The simulated values of Voltage Gain, CMRR and Slew rate for current mirror OTA are 34. 7814 dB, 93. 0159 dB and 18. 705 V/µs respectively, and the values of for telescopic OTA are 48. 74157 dB, 109. 53041 dB and 2. 94 V/µs respectively.

1. R. F. Yazicioglu, S. Kim, T. Torfs, H. Kim, and C. V. Hoof, "A 30 uw analog signal processor asic for portable biopotential signal monitoring," IEEE J. Solid-State Circuits, vol. 46, no. 1, pp. 209–223, 2011.
2. C. Qian, J. Parramon, and E. Sanchez-Sinencio, "A micropower lownoise neural recording front-end circuit for epileptic seizure detection," IEEE J. Solid-State Circuits, vol. 46, no. 6, pp. 1392–1405, 2011.
3. R. R. Harrison, P. T. Watkins, R. J. Kier, R. O. Lovejoy, D. J. Black, B. Greger, and F. Solzbacher, "A low-power integrated circuit for a wireless 100-electrode neural recording system," IEEE J. Solid-StateCircuits, vol. 38, no. 6, pp. 958–965, 2007.
4. C. M. Lopez, D. Prodanov, D. Braeken, I. Gligorijevic,W. Eberle, C. Bartic, R. Puers, and G. Gielen, "Multichannel integrated circuit for electrical recording of neural activity, with independent channel programmability," IEEE Trans. Biomed. Circuits Syst. , vol. 6, no. 2, pp. 101–110, 2012.
5. J. Lee, H. Rhew, D. R. Kipke, and M. P. Flynn, "A 64 channel programmable closed-loop neurostimulator with 8 channel neural amplifier and logarithmic ADC," IEEE J. Solid-State Circuits, vol. 45, no. 9, pp. 1935–1945, 2010.
6. M. Azin, D. J. Guggenmos, S. Barbay, R. J. Nudo, and P. Mohseni, "A battery-powered activity-dependent intracortical microstimulation ic for brain-machine-brain interface," IEEE J. Solid-State Circuits, vol. 46, no. 4, pp. 731–745, 2011.
7. L. C. Stotts, ?Introduction to implantable biomedical IC design,? IEEE Circuits Devices Mag. , pp. 12–18, Jan. 1989.
8. M. R. Dewitt, G. F. Gross, and R. Ramachandran, ?Built-in-self-test for analog to digital converters,? U. S. Patent 5 132 685, Aug. 9, 1991.
9. P. Kinget and M. Steyaert, ?Full analog CMOS integration of very large time constants for synaptic transfer in neural networks,? Analog Integr. Circuits Signal Proces. , vol. 2, pp. 281–295, 1992.
10. Singh, Abhay Pratap, Sunil Kumar Pandey, and Manish Kumar. "Operational Transconductance Amplifier For Low Frequency Application. " International Journal Computer Technology & Applications 3. 3 (2012).
11. Joachim H. Nagel, "THE BIOMEDICAL Engineering Handbook" 2000 by CRC press LLC.
12. Wheatley, C. F. , and H. A. Wittlinger. "OTA obsoletes op. amp. " P. Nat. Econ. Conf. 1969.
13. Harrison, Reid R. , and Cameron Charles. "A low-power low-noise CMOS amplifier for neural recording applications. " Solid-State Circuits, IEEE Journal of 38. 6 (2003): 958-965.
14. Zhang, Fan, Jeremy Holleman, and Brian P. Otis. "Design of ultra-low power biopotential amplifiers for biosignal acquisition applications. " IEEE Transactions on Biomedical Circuits and Systems, Volume 6, No. 4 , pp: 344-355,2012.

Operational Transconductance Amplifier (ota) Current Mirror Ota Telescopic Ota Voltage Gain Common Mode Rejection Ratio (cmrr) Slew Rate.