International Conference on Advances in Computer Engineering and Applications |
Foundation of Computer Science USA |
ICACEA - Number 6 |
April 2014 |
Authors: Ruchi Gupta, Pankaj Agarwal, A.k Soni |
39c702c8-0ba7-4faf-ab12-90c8c57df078 |
Ruchi Gupta, Pankaj Agarwal, A.k Soni . TSGA-MSA: Trace Sequence Algorithm for Alignment of MSA. International Conference on Advances in Computer Engineering and Applications. ICACEA, 6 (April 2014), 21-26.
Multiple sequence alignment (MSA) is an NP-complete and important problem in bioinformatics. In this paper, we have proposed iterative alignment method using a Genetic Algorithm for Multiple Sequence Alignment, named TSGA-MSA. The steps in this algorithm are discussed in details and its performances on a set of benchmark datasets from the BAliBase 2. 0 are analysed. The experimental results, the effects of the initial generation and genetic operators on the performance of this algorithm, the parameter settings, and a comparison of results with other well-known algorithm are presented and discussed.