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Reseach Article

TSGA-MSA: Trace Sequence Algorithm for Alignment of MSA

Published on April 2014 by Ruchi Gupta, Pankaj Agarwal, A.k Soni
International Conference on Advances in Computer Engineering and Applications
Foundation of Computer Science USA
ICACEA - Number 6
April 2014
Authors: Ruchi Gupta, Pankaj Agarwal, A.k Soni
39c702c8-0ba7-4faf-ab12-90c8c57df078

Ruchi Gupta, Pankaj Agarwal, A.k Soni . TSGA-MSA: Trace Sequence Algorithm for Alignment of MSA. International Conference on Advances in Computer Engineering and Applications. ICACEA, 6 (April 2014), 21-26.

@article{
author = { Ruchi Gupta, Pankaj Agarwal, A.k Soni },
title = { TSGA-MSA: Trace Sequence Algorithm for Alignment of MSA },
journal = { International Conference on Advances in Computer Engineering and Applications },
issue_date = { April 2014 },
volume = { ICACEA },
number = { 6 },
month = { April },
year = { 2014 },
issn = 0975-8887,
pages = { 21-26 },
numpages = 6,
url = { /proceedings/icacea/number6/15839-1473/ },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Proceeding Article
%1 International Conference on Advances in Computer Engineering and Applications
%A Ruchi Gupta
%A Pankaj Agarwal
%A A.k Soni
%T TSGA-MSA: Trace Sequence Algorithm for Alignment of MSA
%J International Conference on Advances in Computer Engineering and Applications
%@ 0975-8887
%V ICACEA
%N 6
%P 21-26
%D 2014
%I International Journal of Computer Applications
Abstract

Multiple sequence alignment (MSA) is an NP-complete and important problem in bioinformatics. In this paper, we have proposed iterative alignment method using a Genetic Algorithm for Multiple Sequence Alignment, named TSGA-MSA. The steps in this algorithm are discussed in details and its performances on a set of benchmark datasets from the BAliBase 2. 0 are analysed. The experimental results, the effects of the initial generation and genetic operators on the performance of this algorithm, the parameter settings, and a comparison of results with other well-known algorithm are presented and discussed.

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Index Terms

Computer Science
Information Sciences

Keywords

Genetic Algorithm Multiple Sequence Alignment Dna Etc.