CFP last date
20 January 2025
Reseach Article

Severity Grading of DME from Retina Images: A Combination of PSO and FCM with Bayes Classifier

by Sreejini K. S, V. K. Govindan
International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 81 - Number 16
Year of Publication: 2013
Authors: Sreejini K. S, V. K. Govindan
10.5120/14206-2430

Sreejini K. S, V. K. Govindan . Severity Grading of DME from Retina Images: A Combination of PSO and FCM with Bayes Classifier. International Journal of Computer Applications. 81, 16 ( November 2013), 11-17. DOI=10.5120/14206-2430

@article{ 10.5120/14206-2430,
author = { Sreejini K. S, V. K. Govindan },
title = { Severity Grading of DME from Retina Images: A Combination of PSO and FCM with Bayes Classifier },
journal = { International Journal of Computer Applications },
issue_date = { November 2013 },
volume = { 81 },
number = { 16 },
month = { November },
year = { 2013 },
issn = { 0975-8887 },
pages = { 11-17 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume81/number16/14206-2430/ },
doi = { 10.5120/14206-2430 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-02-06T21:56:33.554518+05:30
%A Sreejini K. S
%A V. K. Govindan
%T Severity Grading of DME from Retina Images: A Combination of PSO and FCM with Bayes Classifier
%J International Journal of Computer Applications
%@ 0975-8887
%V 81
%N 16
%P 11-17
%D 2013
%I Foundation of Computer Science (FCS), NY, USA
Abstract

Diabetic macular edema (DME) is the main cause of visual impairments in patients with diabetic retinopathy and leads to vision loss if left untreated. In this paper, an automatic approach for severity grading of DME is introduced. The approach involves preprocessing, combination of Particle Swarm Optimization (PSO) algorithm and Fuzzy C-Means Clustering for exudates segmentation, optic disc elimination, fovea and macular region localization, and classification. The Bayes classifier separates the lesions to exudates and non-exudates. The severity of the disease is graded into categories such as normal, grade 1 and grade 2 based on the location of exudates. Region of macula is marked by Early Treatment Diabetic Retinopathy Studies (ETDRS) grading scale. The proposed method is evaluated using 200 images of publically available MESSIDOR database and performance figures of 91% for sensitivity, 98% for specificity and 94. 5% for accuracy are obtained.

References
  1. L. Giancardo, F. Meriaudeau, T. P. Karnowski, Y. Li, K. W. Tobin and E. Chaum, "Automatic retina exudates segmentation without a manually labelled training set," Proc. of the 8th IEEE Int. Symp. Biomed. Imag: From Nano to Macro, ISBI 2011, Chicago, USA, pp. 1396 – 1400.
  2. Thomas A. Ciulla, Armando G. Amador and Bernard Zinman, "Diabetic Retinopathy and Diabetic Macular Edema, Pathophysiology," screening, and novel therapies," Diabetes Care, Vol. 26, no. 9, pp. 2653 - 2664, 2003.
  3. Maria Garcia, Roberto Hornero, Clara I. Sanchez, Maria I. Lopez, and Ana Diez, "Feature Extraction and Selection for the Automatic Detection of Hard Exudates in Retinal Images," In Proceedings of the 29th Annual International Conference of the IEEE EMBS, Cite Internationale, Lyon, France, August 23-26, 2007.
  4. Methods to evaluate segmentation and indexing techniques in the field of retinal ophtalmology. [Online 2012]. Available: http://messidor. crihan. fr
  5. Deepak AND Sivaswamy, "Automatic Assessment of Macular Edema From Color Retinal Images," IEEE TRANSACTIONS ON MEDICAL IMAGING, VOL. 31, NO. 3, MARCH 2012.
  6. Maalej A, Cheima W, Asma K, Riadh R, Salem G, "Optical Coherence Tomography for Diabetic Macular Edema: Early Diagnosis, Classification and Quantitative Assessment," J Clinic Experiment Ophthalmol S2:004, 2012.
  7. S. T. Lim, W. M. D. W. Zaki, A. Hussain, S. L. Lim and S. Kusalavan, "Automatic Classification of Diabetic Macular Edema in Digital Fundus Images," In CHUSER 2011, Dec. , Penag.
  8. Early Treatment Diabetic Retinopathy Study Research Group: Treatment techniques and clinical guidelines for photocoagulation of diabetic macular edema. ETDRS Rep. 9. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology. ; 94(7), pp. 761-74, Jul. 1987.
  9. Adam S. Wenick and Neil M. Bressler, "Diabetic Macular Edema: Current and Emerging Therapies," Middle East Afr J Ophthalmol. , Vol. 19, Issue 1, pp. 4 - 12, 2012.
  10. Akara Sopharak , Bunyarit Uyyanonvara, Sarah Barman and Tom Williamson, "Automatic detection of diabetic retinopathy exudates from non-dilated retinal images using mathematical morphology methods," Journal of Computerized Medical Imaging and Graphics, pp. 720 - 727, 2008.
  11. K. Lochan, P. Sah and Sarma K. K. , "Innovative feature set for retinopathic analysis of diabetes and its detection," 2012 3rd National Conference on Emerging Trends and Applications in Computer Science (NCETACS).
  12. Maha S. El-Shahawy, Ahmed ElAntably, Nermin Fawzy, Khaled Samir, Mustafa Hunter and Ahmed S. Fahmy, "Segmentation of Diabetic Macular Edema in Fluorescein Angiograms," IEEE International Symposium on Biomedical Imaging: From Nano to Macro, pp. 661 - 664, 2011.
  13. LGiancardo, F. Meriaudeau, T. Karnowski, K. Tobin, E. Grisan, P. Favaro, A. Ruggeri, and E. Chaum, "Textureless macula swelling detectionwith multiple retinal fundus images," IEEE Trans. Biomed. Eng. , vol. 8, no. 3, pp. 795–799, Mar. 2011.
  14. A. Aquino, M. E. Gegundez-Arias, and D. Marin, "Detecting the optic disc boundary in digital fundus images using morphological, edge detection and feature extraction techniques," IEEE transactions on medical imaging, 29(10), pp: 1860-1869, 2010.
  15. Ahmed Wasif Reza & C. Eswaran & Kaharudin Dimyati, "Diagnosis of Diabetic Retinopathy: Automatic Extraction of optic disk and exudates from retinal images using marker controlled watershed transformation", J. Med. Syst. , 491-1501, 2011.
  16. Thomas Walter, Jean-Claude Klein, Pascale Massin, and Ali Erginay, "A Contribution of Image Processing to the Diagnosis of Diabetic Retinopathy—Detection of Exudates in Color Fundus Images of the Human Retina", IEEE TRANSACTIONS ON MEDICAL IMAGING, VOL. 21, NO. 10, OCTOBER 2002.
  17. C. Sinthanayothin, J. Boyce, H. Cook, and T. Williamson, "Automated localization of the optic disc, fovea, and retinal blood vessels from digital colour fundus images," In British Journal of Ophthalmology, Vol. 83, no. 11, pp. 902 - 910, 1999.
  18. James Kennedy and Russell Eberhart. , "Particle swarm optimization", Proc. of the IEEE International Conference on Neural Networks, Vol. 4, pp. 1942 - 1948, Piscataway, NJ, 1995.
  19. Amanpreet Kaur and M. D. Singh, "An Overview of PSO - Based Approaches in Image Segmentation," IJET, Vol. 2, no. 8, pp. 1349 -1357, 2012.
  20. Pedram Ghamisi, Micael S Couceiro, Jón Atli Benediktsson and Nuno M. F. Ferreira, "An efficient method for segmentation of images based on fractional calculus and natural selection", In International Journal of Expert Systems with Applications, Vol. 39, pp. 12407 -12417, 2012.
  21. Azarbad and Milad, "Brain tissue segmentation using an unsupervised clustering technique based on PSO algorithm", In Iranian Conference of Biomedical Engineering (ICBME), 2010.
  22. Zhou Xian-cheng, "Image Segmentation Based on Modified Particle Swarm Optimization and Fuzzy C-Means Clustering Algorithm", Second International Conference on Intelligent Computation Technology and Automation, 2009.
  23. J. C. Bezdek, "Pattern Recognition with Fuzzy Objective Function Algorithms," Plenum, New York, 1981.
  24. A. Osareh, B. Shadgar and R. Markham, "A Computational-Intelligence-Based Approach for Detection of exudates in Diabetic Retinopathy Images", IEEE transaction on Information Technology in biomedicine, Vol. 13, Issue 4, pp. 535- 545, 2009.
  25. R. Gonzalez and R. Woods, Digital Image Processing, Addison-Wesley Press, 1993.
  26. N. Otsu, "A threshold selection method from gray-level histograms," IEEE Transactions on Systems, Man, Cybernetics, SMC - 9, pp. 62 – 66, 1979.
  27. R. O. Duda, P. E. Hart, and D. G. Stork, "Pattern Classification", San Diego: Harcourt Brace Jovanovich, Second ed. , November 2000.
  28. N. Friedman, D. Geiger, and M. Goldszmidt, "Bayesian network classifiers," Machine Learning. Vol. 29, pp. 131-163, 1997.
  29. Sopharak, Akara, Dailey, Matthew N. , Uyyanonvara, Bunyarit, Barman, Sarah, Williamson, Tom, Nwe, Khine Thet and Moe, Yin Aye , "Machine learning approach to automatic exudate detection in retinal images from diabetic patients", Journal of Modern Optics, 57(2):124-135, 2010.
  30. Early Treatment Diabetic Retinopathy Study research group: Early photocoagulation for diabetic retinopathy. ETDRS Rep. 9. Ophthalmology 98, pp. 766 - 785, 1991.
  31. Sreejini K. S and V. K. Govindan, "Automatic grading of severity of diabetic macular edema using color fundus images", In Proc. of Third International conference on Advances in Computing and Communications (ACC- 2013), Aug. 29-31 at RSET, Kerala.
Index Terms

Computer Science
Information Sciences

Keywords

Exudates FCM Clustering fovea macula PSO segmentation severity of DME