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Reseach Article

Stochastic Model for Genetic Recombination because of Crossing over and Chromatid Exchange

by Jugal Gogoi, Tazid Ali, Rajeev Sharmah
International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 80 - Number 13
Year of Publication: 2013
Authors: Jugal Gogoi, Tazid Ali, Rajeev Sharmah
10.5120/13918-1689

Jugal Gogoi, Tazid Ali, Rajeev Sharmah . Stochastic Model for Genetic Recombination because of Crossing over and Chromatid Exchange. International Journal of Computer Applications. 80, 13 ( October 2013), 1-3. DOI=10.5120/13918-1689

@article{ 10.5120/13918-1689,
author = { Jugal Gogoi, Tazid Ali, Rajeev Sharmah },
title = { Stochastic Model for Genetic Recombination because of Crossing over and Chromatid Exchange },
journal = { International Journal of Computer Applications },
issue_date = { October 2013 },
volume = { 80 },
number = { 13 },
month = { October },
year = { 2013 },
issn = { 0975-8887 },
pages = { 1-3 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume80/number13/13918-1689/ },
doi = { 10.5120/13918-1689 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-02-06T21:54:26.093452+05:30
%A Jugal Gogoi
%A Tazid Ali
%A Rajeev Sharmah
%T Stochastic Model for Genetic Recombination because of Crossing over and Chromatid Exchange
%J International Journal of Computer Applications
%@ 0975-8887
%V 80
%N 13
%P 1-3
%D 2013
%I Foundation of Computer Science (FCS), NY, USA
Abstract

Genetic recombination by crossing over and chromatid exchange in eukaryotes is one of the major events leading to variance, among individuals of a population set. Therefore, quantification of the recombination would be central to the understanding of the genetic diversity, genealogical differences, disease variants and its maintenance within the population. Hence in this article an attempt is made to model genetic recombination stochastically and prove the Haldane's mapping function of genetic recombination by applying exponential series and Poisson process.

References
  1. Hart, D. L. 2000. A Primer of Population Genetics, Sinauer Associates Inc. 3rd edition, 96-98.
  2. Watson, R. A. , Pollack, J. B. 2000. Combination and Recombination in a Genetic Algorithm. Dynamical and Evolutionary Machine Organization Group .
  3. Weiller, G. F. 1998. Phylogenetic profile: a graphical method for detecting genetic recombinations in homologous sequences. Molecular Biology and Evolution (15), 326-335.
  4. Etherington, G. J. , Dicks, J. and Roberts, I. N. 2005. Recombination Analysis Tool (RAT): a program for the high-throughput detection of recombination. Bioinformatics (21), 278-281.
  5. Sawyer. 1989. Statistical tests for detecting gene conversion. Molecular Biology and Evolution (6), 526-538.
  6. Jakobsen, I. B. and Easteal, S. 1996. A program for calculating and displaying compatibility matrices as an aid in determining reticulate evolution in molecular sequences. Computer applications in the Biosciences (12), 291-295.
  7. Bruen, T. C. , Philippe, H. and Bryant, D. 2006. A simple and robust statistical test for detecting the presence of recombination. Genetics (172), 2665-2681.
  8. Hein (1990): Reconstructing evolution of sequences subject to recombination using parsimony. Mathematical Biosciences (98), 185-200.
  9. Haldane, J. B. S . 1919. Journal of Genetics (8), 299-309.
  10. Ross, S. M. 1995. Stochastic Processes. Wiley. 2nd edition.
  11. Kingman; Charles, John Frank . 1992. Poisson processes. Vol. 3. Clarendon Press.
  12. Bernstein, H and Bernstein, C. 2010. Evolutionary origin of recombination during meiosis. BioScience 60(7), 498-505.
  13. Cobbs, G. 1978. Renewal process approach to the theory of Genetic linkage: case of no chromatid interference, Journal of Theory of Genetic Linkage . Genetics 139.
  14. Van der Vaart, A. W. 2008. Statistics in Genetics, Chapters 1,2,11.
  15. Liu, B. H . 1997. Statistica Genomics: Linkage, Mapping, and QTL Analysis. CRC Press. 18-19.
Index Terms

Computer Science
Information Sciences

Keywords

Gene Crossing-over Recombination mutation stochastic model.