CFP last date
20 December 2024
Reseach Article

A Case Study of Parkinson’s Disease Diagnosis using Artificial Neural Networks

by Farhad Soleimanian Gharehchopogh, Peyman Mohammadi
International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 73 - Number 19
Year of Publication: 2013
Authors: Farhad Soleimanian Gharehchopogh, Peyman Mohammadi
10.5120/12990-9206

Farhad Soleimanian Gharehchopogh, Peyman Mohammadi . A Case Study of Parkinson’s Disease Diagnosis using Artificial Neural Networks. International Journal of Computer Applications. 73, 19 ( July 2013), 1-6. DOI=10.5120/12990-9206

@article{ 10.5120/12990-9206,
author = { Farhad Soleimanian Gharehchopogh, Peyman Mohammadi },
title = { A Case Study of Parkinson’s Disease Diagnosis using Artificial Neural Networks },
journal = { International Journal of Computer Applications },
issue_date = { July 2013 },
volume = { 73 },
number = { 19 },
month = { July },
year = { 2013 },
issn = { 0975-8887 },
pages = { 1-6 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume73/number19/12990-9206/ },
doi = { 10.5120/12990-9206 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-02-06T21:40:29.626392+05:30
%A Farhad Soleimanian Gharehchopogh
%A Peyman Mohammadi
%T A Case Study of Parkinson’s Disease Diagnosis using Artificial Neural Networks
%J International Journal of Computer Applications
%@ 0975-8887
%V 73
%N 19
%P 1-6
%D 2013
%I Foundation of Computer Science (FCS), NY, USA
Abstract

Artificial Neural Network (ANN)-based diagnosis of medical diseases has been taken into great consideration in recent years. In this paper, two types of ANNs are used to classify effective diagnosis of Parkinson's disease. Multi-Layer Perceptron (MLP) with back-propagation learning algorithm and Radial Basis Function (RBF) ANNs were used to differentiate between clinical variables of samples (N = 195) who were suffering from Parkinson's disease and who were not. For this purpose, Parkinson's disease data set, taken from UCI machine learning database was used. Mean squared normalized error function was used to measure the usefulness of our networks during trainings and direct performance calculations. It was observed that MLP is the best classi?cation with 93. 22% accuracy for the data set. Also, we got 86. 44% accuracy in RBF classification for the same data set. This technique can assist neurologists to make their ultimate decisions without hesitation and more astutely.

References
  1. Hoglinger GU, Rizk P,MurielMP, Duyckaerts C, OertelWH, Caille I, et al. Dopamine depletion impairs precursor cell proliferation in Parkinson disease. Nat Neurosci, Vol: 7, pp: 726–735, 2004.
  2. Aziz, T. Z. , Peggs, D. , Sambrook, M. A. , & Crossman, A. R. , Lesion of the sub thalamic nucleus for the alleviation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism in the primate. Movement Disorders, Vol: 6, No:4, Pp:228–292, 1992.
  3. Khemphila A, Boonjing V. Parkinsons Disease Classi?cation using Neural Network and Feature selection. World Academy of Science, Engineering and Technology, Vol: 64, pp:15-18, 2012.
  4. Farhad Soleimanian Gharehchopogh, Peyman Mohammadi and Parvin Hakimi. Application of Decision Tree Algorithm for Data Mining in Healthcare Operations: A Case Study. International Journal of Computer Applications, Vol: 52, No:6, PP:21-26, August 2012.
  5. Valluru B. Rao and Hayagriva Rao. 1995. C++, Neural Networks and Fuzzy Logic (2nd Ed. ). MIS: Press, New York, NY, USA.
  6. Alexander I. Galushkin. 2007. Neural Network Theory. Springer-Verlag New York, Inc. , Secaucus, NJ, USA.
  7. Shigeo Oyagi, Ryoichi Mori, Noriaki Sanechika Realization of a Boolean function using an extended threshold logic. Bulletin of the Electro technical Laboratory, Vol: 42, PP: 9–74, 1978.
  8. I. A. Basheer, M. Hajmeer, Artificial neural networks: fundamentals, computing, design, and application, J. Microbiol. Meth. Vol:43, PP: 3–31, 2000.
  9. B. B. Chaudhuri, U. Bhattacharya, ENcient training and improved performance of multilayer perceptron in pattern classification, Neurocomputing, Vol:34, pp: 11-27, 2000.
  10. Hanbay, D. , Turkoglu, I. , & Demir, Y. (2008). An expert system based on wavelet decomposition and neural network for modeling Chua's circuit. Expert Systems with Applications, Vol: 34, No:4, Pp: 2278–2283.
  11. Tran Nguyen, Richard Malley, Stanley H. Inkelis, Nathan Kuppermann, Comparison of prediction models for adverse outcome in pediatric meningococcal disease using artificial neural network and logistic regression analyses, Journal of Clinical Epidemiology, Vol: 55, No: 7, Pp: 687-695, 2002
  12. Parbhane, R. V. , Tambe, S. S. , Kulkarni, B. D. , ANN modeling of DNA sequences: New strategies using DNA shape code, Computer. Chem. Vol: 24, Pp: 699-711, 2000.
  13. Tafeit, E. , Reibnegger, G. , Artificial neural networks in laboratory medicine and medical outcome prediction. Clin. Chem. Lab. Med. Vol: 37, Pp: 845-853, 1999.
  14. Kenji S. , Artificial Neural Networks - Methodological Advances and Biomedical Applications. IN-TECHJaneza Trdine 9, 51000 Rijeka, Croatia, April, 2011.
  15. Sarah L. Gulliford, Steve Webb, Carl G. Rowbottom, David W. Corne, David P. Dearnaley, Use of artificial neural networks to predict biological outcomes for patients receiving radical radiotherapy of the prostate, Radiotherapy and Oncology, Vol: 71, No:1, PP 3-12, 2004.
  16. Daniel Ansari, Johan Nilsson, Roland Andersson, Sara Regnér, Bobby Tingstedt, Bodil Andersson, Artificial neural networks predict survival from pancreatic cancer after radical surgery, The American Journal of Surgery, Vol: 205, No: 1, Pp: 1-7, 2013.
  17. Shiek S. S. J. Ahmed, Winkins Santosh, Suresh Kumar, T. Hema Thanka Christlet, Neural network algorithm for the early detection of Parkinson's disease from blood plasma by FTIR micro-spectroscopy, Vibrational Spectroscopy, Vol: 53, No:2, Pp: 181-188, 2010.
  18. Parkinson's Data Set, UCI repository of machine learning databases available from ftp://ftp. ics. uci. edu/ pub/machine-learning-databases/parkinsons/parkinsons . data, [last accessed: 27 April 2013].
  19. K. , Warwick, Arti?cial intelligence: The basics. Taylor & Francis, 2011.
  20. D. S. Broomhead and D. Lowe. Multivariate functional interpolation and adaptive networks. Complex Systems, Vol: 2, Pp: 321-355, 1988.
  21. Wu, D. , Warwick, K. , Ma, Z. , Burgess, J. G. , Pan, S. , & Aziz, T. Z. , Prediction of Parkinson's disease tremor onset using radial basis function neural networks. Expert Systems with Applications, Vol: 37, No: 4, Pp: 2923–2928, 2010.
  22. Song Pan, Serdar Iplikci, Kevin Warwick, Tipu Z. Aziz, Parkinson disease tremor 's classification – A comparison between Support Vector Machines and neural networks, Expert Systems with Applications, Vol: 39, No: 12, Pp: 10764-10771, 2012
Index Terms

Computer Science
Information Sciences

Keywords

Parkinson's disease Artificial Neural Network Multi-layer Perceptron Radial Basis Function