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Article:Comparative Study of Ligand Docking

by M.Naresh Babu, Patchikolla Satheesh, R S Datta Teja Grandhi, Prof. Allam Appa Rao
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International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 6 - Number 1
Year of Publication: 2010
Authors: M.Naresh Babu, Patchikolla Satheesh, R S Datta Teja Grandhi, Prof. Allam Appa Rao
10.5120/1045-1355

M.Naresh Babu, Patchikolla Satheesh, R S Datta Teja Grandhi, Prof. Allam Appa Rao . Article:Comparative Study of Ligand Docking. International Journal of Computer Applications. 6, 1 ( September 2010), 36-39. DOI=10.5120/1045-1355

@article{ 10.5120/1045-1355,
author = { M.Naresh Babu, Patchikolla Satheesh, R S Datta Teja Grandhi, Prof. Allam Appa Rao },
title = { Article:Comparative Study of Ligand Docking },
journal = { International Journal of Computer Applications },
issue_date = { September 2010 },
volume = { 6 },
number = { 1 },
month = { September },
year = { 2010 },
issn = { 0975-8887 },
pages = { 36-39 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume6/number1/1045-1355/ },
doi = { 10.5120/1045-1355 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-02-06T19:54:17.567715+05:30
%A M.Naresh Babu
%A Patchikolla Satheesh
%A R S Datta Teja Grandhi
%A Prof. Allam Appa Rao
%T Article:Comparative Study of Ligand Docking
%J International Journal of Computer Applications
%@ 0975-8887
%V 6
%N 1
%P 36-39
%D 2010
%I Foundation of Computer Science (FCS), NY, USA
Abstract

Anti-apoptotic proteins play an vital role in deactivating the apoptosis process in cancer disease. Apoptosis process can be activated in cancer state by inhibiting anti-apoptotic proteins. Apoptosis occurs via 2 main signalling pathways the Intrinsic and Extrinsic pathways. Extrinsic pathway is regulated by p53 protein, cyt c and apaf-1 regulates the intrinsic pathway. A class of caspase cascades(2,3,6,7,8,9) helps in induction, transduction, amplification and execution of apoptotic signals in intrinsic and extrinsic signalling pathways.

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Index Terms

Computer Science
Information Sciences

Keywords

Computer Science Computer Engineering Interdisciplinary Research Diabetes mellitus Rigid Docking anti apoptotic proteins

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