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Reseach Article

Optimization of h-Glucan Production from Lower Fungi using Central Composite Design and its Biological Application

by Balaji Paulraj, T. Saravanan
International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 49 - Number 8
Year of Publication: 2012
Authors: Balaji Paulraj, T. Saravanan
10.5120/7647-0737

Balaji Paulraj, T. Saravanan . Optimization of h-Glucan Production from Lower Fungi using Central Composite Design and its Biological Application. International Journal of Computer Applications. 49, 8 ( July 2012), 23-28. DOI=10.5120/7647-0737

@article{ 10.5120/7647-0737,
author = { Balaji Paulraj, T. Saravanan },
title = { Optimization of h-Glucan Production from Lower Fungi using Central Composite Design and its Biological Application },
journal = { International Journal of Computer Applications },
issue_date = { July 2012 },
volume = { 49 },
number = { 8 },
month = { July },
year = { 2012 },
issn = { 0975-8887 },
pages = { 23-28 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume49/number8/7647-0737/ },
doi = { 10.5120/7647-0737 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-02-06T20:45:44.493589+05:30
%A Balaji Paulraj
%A T. Saravanan
%T Optimization of h-Glucan Production from Lower Fungi using Central Composite Design and its Biological Application
%J International Journal of Computer Applications
%@ 0975-8887
%V 49
%N 8
%P 23-28
%D 2012
%I Foundation of Computer Science (FCS), NY, USA
Abstract

Production of ?-glucan is mainly used for cancer therapy. The most well-known are those occur in fungal grains such as cereal and other micro-organisms. The most important beta glucan from a nutritional and ingredient standpoint is that derived from fungal grain. Optimization of medium ingredients for the production of mycelial ?-glucan from lower fungi in submerged fermentation and antioxidant activity of ?-glucan was carried out.

References
  1. G. D. Ross, V. Vetvicka, J. Yan, Y. Xia, J. Vetvicková, Therapeutic intervention with complement and b-glucan in cancer, Immunopharmacology 42 (1999) 61–74
  2. K. Y. Lee, M. H. Lee, I. Y. Chang, S. P. Yoon, D. Y. Lim, Y. J. Jeon, Macrophage activation by polysaccharide fraction isolated from Salicornia herbacea, J. Ethnopharmacol. 103 (2006) 372–378
  3. Z. Wang, D. Luo, Antioxidant activities of different fractions of polysaccharide puri?ed from Gynostemma pentaphyllum Makino, Carbohydr. Polym. 68 (2007) 54–58.
  4. M. K. Kim, I. Y. Lee, J. H. Ko, Y. H. Rhee, Y. H. Park, Higher intracellular levels of uridine monophosphate under nitrogen-limited conditions enhance the metabolic ?ux of curdlan synthesis in Agrobacterium species, Biotechnol. Bioeng. 62 (1999) 317–323.
  5. P. C. K. Cheung. The hypocholesterolemic effect of extracellular polysaccharidefrom the submerged fermentation of mushroom. Nutri. Res. 16 (1996) 1953–1957.
  6. S. W. Kim, H. J. Hwang, C. P. Xu, Y. S. Na, S. K. Song, J. W. Yun, In?uence of nutritional conditions on mycelial growth and exopolysaccharide production in Paecilomyces sinclairii, Lett. Appl. Microbiol. 34 (2002) 389–393.
  7. J. H. Xiao, D. X. Chen, W. H. Wan, X. J. Hu, Y. Qi, Z. Q. Liang, Enhanced simultaneous the production of mycelia and intracellular polysaccharide in submerged cultivation of Cordyceps jiangxiensis using desirability functions, Process Biochem. 41 (2006) 1887–1893.
  8. V. K. Lowry, M. B. Farnell, P. J. Ferro, C. L. Swaggerty, A. Bahl, M. H. Kogut. Purified ?-glucan as an abiotic feed additive up-regulates the innate immune response in immature chickens against Salmonella enterica serovar Enteritidis. Int. J. Food Microbiology. 98 (2005) 309-318.
  9. J. J. Volman, J. D. Ramakers, J. Plat. Dietary modulation of immune function by ?-glucans. Physiol. Behavior 94 (2008) 276-284.
  10. Jun Liu, Jianguang Luo, Hong Ye, Yi Sun, Zhaoxin Lu, Xiaoxiong Zeng. Production, characterization and antioxidant activities invitro of exopolysaccharides from endophytic bacterium Paenibacillus polymyxa EJS-3. Carbohydrate Polymers, 78 (2009) 275-281.
  11. W. Brand Williams, M. E. Cuvelier, C. Berset. Use of a free radical method to evaluate antioxidant activity. Lebensm. Wiss. Technol. 28 (1995) 25-30.
  12. C. Sanchez Moreno, J. A. Larrauri, F. A. Saura Calixto. A procedure to measure the antiradical efficiency of polyphenols. J. Sci. Food Agric. 76 (1998) 270-276.
Index Terms

Computer Science
Information Sciences

Keywords

?-glucan CCD RSM FTIR Antioxidant activity