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Mechanism of RNAi in Genomics and Therapeutics: A Review

by Reena Murali, David Peter. S
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International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 48 - Number 4
Year of Publication: 2012
Authors: Reena Murali, David Peter. S
10.5120/7337-0062

Reena Murali, David Peter. S . Mechanism of RNAi in Genomics and Therapeutics: A Review. International Journal of Computer Applications. 48, 4 ( June 2012), 21-24. DOI=10.5120/7337-0062

@article{ 10.5120/7337-0062,
author = { Reena Murali, David Peter. S },
title = { Mechanism of RNAi in Genomics and Therapeutics: A Review },
journal = { International Journal of Computer Applications },
issue_date = { June 2012 },
volume = { 48 },
number = { 4 },
month = { June },
year = { 2012 },
issn = { 0975-8887 },
pages = { 21-24 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume48/number4/7337-0062/ },
doi = { 10.5120/7337-0062 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-02-06T20:43:13.764850+05:30
%A Reena Murali
%A David Peter. S
%T Mechanism of RNAi in Genomics and Therapeutics: A Review
%J International Journal of Computer Applications
%@ 0975-8887
%V 48
%N 4
%P 21-24
%D 2012
%I Foundation of Computer Science (FCS), NY, USA
Abstract

RNA interference (RNAi) has the potential to address gene regulatory role in an efficient manner. Short interfering RNA (siRNA), the small RNA deriving from RNAi can control the gene regulation, by a technique called gene silencing. Gene silencing is "switching off" genes which are over expressed, in a sequence specific manner. SiRNA has been experimentally studied in disease therapy and is expected to be developed as a nucleic acid based medicine for incurable diseases such as cancer. This paper reviews the mechanism of RNAi as a gene regulator in genomics and therapeutics.

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Index Terms

Computer Science
Information Sciences

Keywords

Double Stranded Rna (dsrna) Short Interfering Rna (sirna) Rna Interference (rnai) Gene Regulation Gene Silencing

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