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Reseach Article

Heart Rate Variability Analysis a Non-invasive Clinical Screening Tool to Detect Functional Ability of Diabetic Cardiac Autonomic Neuropathy

by Sarika Tale, T.R.Sontakke
International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 25 - Number 10
Year of Publication: 2011
Authors: Sarika Tale, T.R.Sontakke
10.5120/3145-4342

Sarika Tale, T.R.Sontakke . Heart Rate Variability Analysis a Non-invasive Clinical Screening Tool to Detect Functional Ability of Diabetic Cardiac Autonomic Neuropathy. International Journal of Computer Applications. 25, 10 ( July 2011), 47-51. DOI=10.5120/3145-4342

@article{ 10.5120/3145-4342,
author = { Sarika Tale, T.R.Sontakke },
title = { Heart Rate Variability Analysis a Non-invasive Clinical Screening Tool to Detect Functional Ability of Diabetic Cardiac Autonomic Neuropathy },
journal = { International Journal of Computer Applications },
issue_date = { July 2011 },
volume = { 25 },
number = { 10 },
month = { July },
year = { 2011 },
issn = { 0975-8887 },
pages = { 47-51 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume25/number10/3145-4342/ },
doi = { 10.5120/3145-4342 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-02-06T20:11:29.043344+05:30
%A Sarika Tale
%A T.R.Sontakke
%T Heart Rate Variability Analysis a Non-invasive Clinical Screening Tool to Detect Functional Ability of Diabetic Cardiac Autonomic Neuropathy
%J International Journal of Computer Applications
%@ 0975-8887
%V 25
%N 10
%P 47-51
%D 2011
%I Foundation of Computer Science (FCS), NY, USA
Abstract

Cardiovascular complications are the main cause of death in people with diabetes, which if identified can lead to improved health. A non-invasive, clinical system for low-cost screening of diabetes mellitus (DM) is introduced and tested on patients with some known conditions. Data recorded on 20 Normal Control (NC) and 20 Diabetic mellitus. Lead II electrocardiogram (ECG) was recorded in three modes, supine, sitting to standing and deep breath. The heart rate variability (HRV) signal is extracted from ECG recording. The HRV signal is then characterized using time domain and frequency domain analysis method which is subsequently used as a basis for detection of percentage functional ability of sympathetic, parasympathetic and autonomic nervous system of diabetes mellitus. Almost 20 time domain and frequency domain parameters have significance p-value less than 0.05.Poor heart rate variability is seen in diabetes patients in all three modes. In patients with type 2 DM significant reduction of spectral power in HF band of the heart rate variability was found for orthostatic stress and respiratory stress. Decreased values of Dynamic Orthostatic Stress (DOS) index, Dynamic Respiratory Stress (DRS) index and Ortho-Respiratory Stress (ROR) Index for DM compared to NC indicates damage to sympathetic, parasympathetic and autonomic nervous system of DM as an effect of diabetes.

References
  1. Task Force of the European Society of Cardiology the North American Society of Pacing and Electrophysiology “Heart rate variability: standards of measurement, physiological interpretation and clinical use”. Circulation, 1996; 93:1043–1065.
  2. Juha-Pekka Niskanen, Mika P Tarvainen, Perttu O Ranta-aho, Pasi A Karjalainen, “Software for advanced HRV analysis”. Computer Methods and Programs in Biomedicine, 2004; 76, 73-81.
  3. Yonglin Shen, Ke Jiang et.al., “ HRV analyses system based on Windows 95 and its Preliminary exploration for analyzing Diabetics”. In Proc. of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1998; vol. 20, No.1.
  4. M. L. Jacobson, “Non-invasive clinical screening of diabetes and coronary heart disease”. In Proc. of the 4th Annual IEEE Conference on Information Technology applications in Biomedicine, UK. 2003. Vol 32, 226-229.
  5. Selvin E, Marinopoulos S, Berkenblit G, Rami T, Brancati F L, Powe N R. “Meta-analysis: glycosylated hemoglobin and cardiovascular disease in diabetes mellitus”. Ann Intern Med, 2004; 141:421-31.
  6. Gerstein H C, Pogue J, Mann J F, Lonn E, Dagenais G R, McQueen M. “The relationship between dysglycaemia and cardiovascular and renal risk in diabetic and non-diabetic participants in the HOPE study: a prospective epidemiological analysis”. Diabetologia, 2005; 48:1749-55.
  7. Stratton I M, Adler A I, Neil H A, Matthews D R, Manley S E, Cull C A. “Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study”. BMJ, 2000; 321:405-12.
  8. Goff D C, Gerstein H C, Ginsberg H N, Cushman W C, Margolis K L, Byington R P. “Prevention of cardiovascular disease in persons with type 2 diabetes mellitus: current knowledge and rationale for the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial”. Am J Cardiol, 2007; 99:4i-20i.
  9. Dipali Bansal. et.al., “A Review of Measurement and Analysis of Heart Rate Variability”. In Proc. International Conference on Computer and Automation Engineering, 2009.
  10. A Heitmann, T Huebner, R Schroeder, S Perz and A Voss. “Ability of Heart Rate Variability as Screening Tool for Heart Diseases in Man”. Computers in Cardiology, 2009; 36:825−828.
  11. Chengyu Liu, Changchun Liu, Liping Li, Qingguang Zhang, Bin Li. “Systolic and Diastolic Time Interval Variability Analysis and Their Relations with Heart Rate Variability”. IEEE, 2009; 978-1-4244-2902-8:1-4.
  12. Bert-Uwe Kohler, Carsten Henning, Reinhold Orglmeister, “The Principles of Software QRS detection”. In IEEE Engineering in Medicine and Biology magazine, 2002.
  13. S S Mehta et al. “Computer-aided interpretation of ECG for diagnostics”. Int. Journal of System Science, 1996; 43-58.
  14. D Benitez. et al. “The use of Hilbert transform in ECG signal analysis”. Comp. in Bio. and Med, 2001; 31:399-406.
  15. S C Saxena. et al. “Feature extraction from ECG signals using wavelet transform for disease diagnostics”. Int. Journal of System Science, 2002; 33:1073- 1085.
  16. M. Engin. “ECG beat classification using neuro-fuzzy network”. Pat. Rec. Letters, 2004; 25:1715-1722.
  17. N M Arzeno, Z D Deng and C S Poon. “Analysis of first derivative based QRS detection algorithms,” IEEE Transactions on Biomedical Engineering, 2008; vol. 55, 478-484.
  18. Mel M S Ho, Tor S. Lande and Christopher Toumazou. “Efficient Computation of the LF/HF Ratio in Heart Rate Variability Analysis Based on Bitstream Filtering.” IEEE, 2007; 1-4244-1525: 17-20.
  19. Tran Thong. “Real-time Evaluation of Spectral Heart Rate Variability.” IEEE, 2006; 1-4244-0033-3:1768-1771.
  20. E. Jovanov. On Spectral Analysis of Heart Rate Variability during Very Slow Yogic Breathing. IEEE, 2005; 0-7803-8740-6: 2467-2470.
  21. Alam M K, Begum N, Begum S. “Parasympathetic Nerve Functions in Type 2 Diabetes Mellitus: Relation to Glycemic Status and Duration of Diabetes “, Jour Bangladesh Soc Physiol, 2008; (3):42-49.
Index Terms

Computer Science
Information Sciences

Keywords

Heart Rate Variability Diabetes Mellitus Time Domain Analysis Frequency Domain Analysis