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Reseach Article

Protein Function Prediction using Nearer Neighbor Proteins Interactions

by Saima Khan, Saifuddin Md. Tareeq
International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 186 - Number 17
Year of Publication: 2024
Authors: Saima Khan, Saifuddin Md. Tareeq
10.5120/ijca2024923555

Saima Khan, Saifuddin Md. Tareeq . Protein Function Prediction using Nearer Neighbor Proteins Interactions. International Journal of Computer Applications. 186, 17 ( Apr 2024), 15-22. DOI=10.5120/ijca2024923555

@article{ 10.5120/ijca2024923555,
author = { Saima Khan, Saifuddin Md. Tareeq },
title = { Protein Function Prediction using Nearer Neighbor Proteins Interactions },
journal = { International Journal of Computer Applications },
issue_date = { Apr 2024 },
volume = { 186 },
number = { 17 },
month = { Apr },
year = { 2024 },
issn = { 0975-8887 },
pages = { 15-22 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume186/number17/protein-function-prediction-using-nearer-neighbor-proteins-interactions/ },
doi = { 10.5120/ijca2024923555 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-04-27T03:06:53.400201+05:30
%A Saima Khan
%A Saifuddin Md. Tareeq
%T Protein Function Prediction using Nearer Neighbor Proteins Interactions
%J International Journal of Computer Applications
%@ 0975-8887
%V 186
%N 17
%P 15-22
%D 2024
%I Foundation of Computer Science (FCS), NY, USA
Abstract

Protein is one of the most important elements of life. It is responsible for structuring organs, regulating various activities of human body, transporting materials throughout the body etc.Wet lab based experiments for determining protein functions are time consuming, difficult and expensive. Computational methods have got high demands in predicting the functions of proteins because these methods save a significant amount of time and are easier and less expensive than wet lab-based experiments. There are various approaches of predicting protein functions using computational methods. In this study, a novel idea has been proposed to predict the functions of proteins using protein-protein interaction network. This method is based on k-means clustering algorithm, nearer neighbor proteins functions and also the common neighbor proteins functions.

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Index Terms

Computer Science
Information Sciences
protein
neighbor protein
prediction

Keywords

protein-protein interaction network (PPI) k-means clustering algorithm support common neighbor second degree neighbor protein function prediction