CFP last date
20 December 2024
Reseach Article

Performance Analysis of SVM Classification Model for Diagnosis of Alzheimer’s Disease

by Rajasree R.S., S. Brintha Rajakumari, Gajanan Babhulkar, Madhuri Gurale
International Journal of Computer Applications
Foundation of Computer Science (FCS), NY, USA
Volume 174 - Number 27
Year of Publication: 2021
Authors: Rajasree R.S., S. Brintha Rajakumari, Gajanan Babhulkar, Madhuri Gurale
10.5120/ijca2021921144

Rajasree R.S., S. Brintha Rajakumari, Gajanan Babhulkar, Madhuri Gurale . Performance Analysis of SVM Classification Model for Diagnosis of Alzheimer’s Disease. International Journal of Computer Applications. 174, 27 ( Mar 2021), 37-40. DOI=10.5120/ijca2021921144

@article{ 10.5120/ijca2021921144,
author = { Rajasree R.S., S. Brintha Rajakumari, Gajanan Babhulkar, Madhuri Gurale },
title = { Performance Analysis of SVM Classification Model for Diagnosis of Alzheimer’s Disease },
journal = { International Journal of Computer Applications },
issue_date = { Mar 2021 },
volume = { 174 },
number = { 27 },
month = { Mar },
year = { 2021 },
issn = { 0975-8887 },
pages = { 37-40 },
numpages = {9},
url = { https://ijcaonline.org/archives/volume174/number27/31847-2021921144/ },
doi = { 10.5120/ijca2021921144 },
publisher = {Foundation of Computer Science (FCS), NY, USA},
address = {New York, USA}
}
%0 Journal Article
%1 2024-02-07T00:23:16.067143+05:30
%A Rajasree R.S.
%A S. Brintha Rajakumari
%A Gajanan Babhulkar
%A Madhuri Gurale
%T Performance Analysis of SVM Classification Model for Diagnosis of Alzheimer’s Disease
%J International Journal of Computer Applications
%@ 0975-8887
%V 174
%N 27
%P 37-40
%D 2021
%I Foundation of Computer Science (FCS), NY, USA
Abstract

Alzheimer’s disease (AD) is a type of Dementia which affects the brain and causes memory loss. It disrupts a person’s ability to function independently. In this paper we have considered some measures such as Age, MMSE scores, whole brain volume and endocrinal volume. In our work, we have proposed a classification model using SVM model and anlaysed the performance of SVM model for different kernel methods. Moreover a five fold cross validation approach is used to improve the performance oof the model. The results shows that linear and polynomial kernel methods give a classification accuracy of 73.2% and AUC of 0.7.

References
  1. G. McKhann et al., “Clinical diagnosis of Alzheimer’s disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services task force on Alzheimer’s disease,”
  2. Neurology, vol. 34, no. 7, pp. 939–939, 1984.humanbrainsNeuroimage. (2001) 14:21–36. 10.1006/nimg.2001.0786
  3. Valizadeh S, Hänggi J, Mérillat S, Jäncke L. Age prediction on the basis of brain anatomical measures. Hum Brain Mapp. (2017) 38:997–1008. 10.1002/hbm.23434
  4. Fjell AM, Westlye LT, Amlien I, Espeseth T, Reinvang I, Raz N, et al. . High consistency of regional cortical thinning in aging across multiplesamples. CerebCortex. (2009) 19:2001–12. 10.1093/cercor/bhn232
  5. Lin L, Jin C, Fu Z, Zhang B, Bin G, Wu S. Predicting healthy older adult's brain age based on structural connectivity networks using artificial neural networks. Comput Methods ProgramsBiomed. (2016) 125:8–17. 10.1016/j.cmpb.2015.11.012
  6. Nagesh Adluru, Cole H. Korponay, Derek L. Norton, Robin I. Goldman & Richard J. Davidson (2020): BrainAGE and regional volumetric analysis of a Buddhist monk: a longitudinal MRI case study, Neurocase
  7. Jing Wan, Zhilin Zhang, Bhaskar D. Ra ,Shiaofen Fang, Jingwen Yan, Andrew J. Saykin, Li She ,”Identifying the Neuroanatomical Basis of Cognitive Impairment in Alzheimer’s Disease by Correlation and Nonlinearity-Aware Sparse Bayesian Learning”, IEEE Transactions On Medical Imaging, Vol. 33, No. 7, July 2014
  8. Cyrus Raji, James Becker,Owen Thomas Carmichael,”Age, Alzheimers Disease and Brain Structure”, Article  in  Neurology · October 2009, DOI: 10.1212/WNL.0b013e3181c3f293,Source: PubMed
  9. Panagiota Papapostolou, F Goutsaridou, M Arvaniti,” Is Total Brain Volume Correlated to Cognitive Function and Education in Patients with Alzheimer Disease?” Volume: 21 issue: 4, page(s): 500-504 DOI: 10.1177/197140090802100405
  10. Aydin Saribudak, Adarsha A Subick, Na Hyun Kim, Joshua A Rutta, M UmitUyar, “Gene Expressions, Hippocampal Volume Loss, and MMSE Scores in Computation of Progression and Pharmacologic Therapy Effects for Alzheimer's Disease” IEEE/ACM Trans Comput Biol Bioinformdoi: 10.1109/TCBB.2018.2870363. Epub 2018 Sep 14.
  11. VirajAdduru, Stefi Baum, Maria Helguera, RaminZand ,” A Method to Estimate Brain Volume from Head CT Images and Application to Detect Brain Atrophy in Alzheimer Disease”,  American Journal of Neuroradiology · January 2020, DOI: 10.3174/ajnr.A6402
  12. C. Plant et al., “Automated detection of brain atrophy atterns based on MRI for the prediction of Alzheimer’s disease,” Neuroimage, vol. 50, no. 1, pp. 162–174, 2010.
  13. M. Radanovic et al., “White matter abnormalities associated with Alzheimer’s disease and mild cognitive impairment: A critical review of MRI studies,” Expert Rev. Neurotherapeut., vol. 13, no. 5, pp. 483–493, 2013.
  14. A. Chincarini et al., “Alzheimers disease markers from structural MRI and FDG-PET brain images,” Eur. Phys. J. Plus, vol. 127, no. 11, pp.1–16, 2012.
  15. Amira Ben Rabeh, BenzartiFaouzi, Hamid Amiri“Diagnosis of Alzheimer Diseases in Early Step Using SVM (Support Vector Machine)” 13th International Conference on Computer Graphics, Imaging and Visualization (CGiV), DOI 10.1109/CGiV.2016.76.
  16. Ramesh Kumar Lama,1,2 Jeonghwan Gwak,1,3 Jeong-Seon Park,4 and Sang-WoongLee ,” Diagnosis of Alzheimer’s Disease Based on Structural MRI Images Using a Regularized Extreme Learning Machine and PCA Features” Hindawi Journal of Healthcare Engineering Volume 2017, Article ID 5485080, 11 pages https://doi.org/10.1155/2017/5485080.
Index Terms

Computer Science
Information Sciences

Keywords

Alzheimer’s Disease (AD) MiniMental State Examination (MMSE) Dementia Support Vector Machine(SVM)